Publikationsliste

Functional analyses of Src-like adaptor (SLA), a glucocorticoid-regulated gene in acute lymphoblastic leukemia.

Mansha M, Carlet M, Ploner C, Gruber G, Wasim M, Wiegers GJ, Rainer J, Geley S, Kofler R.

Leukemia Research 1 Apr 2010; 34(4)529-34.

Atorvastatin attenuates murine anti-glomerular basement membrane glomerulonephritis.

Eller P, Eller K, Wolf AM, Reinstadler SJ, Tagwerker A, Patsch JR, Mayer G, Rosenkranz AR.

Kidney Int 1 Mar 2010; 77(5)428-35.

CCR7 deficiency exacerbates injury in acute nephritis due to aberrant localization of regulatory T cells.

Eller K, Weber T, Pruenster M, Wolf AM, Mayer G, Rosenkranz AR, Rot A.

J Am Soc Nephrol 1 Jan 2010; 21(1)42-52.

A benefit-risk assessment of imatinib in chronic myeloid leukaemia and gastrointestinal stromal tumours

Wolf D, Rumpold H.

Drug Saf. 2009 1 Dec 2009; 32(11)1001-15.

PKCtheta and Itk functionally interact during primary mouse CD3+ T cell activation.

Thuille N, Lutz-Nicoladoni C, Letschka T, Hermann-Kleiter N, Heit I, Baier G.

Immunology Letters 22 Nov 2009; 126(1-2)54-9.

Gene therapy with the angiogenic cytokine secretoneurin induces therapeutic angiogenesis by a nitric oxide-dependent mechanism.

Schgoer W, Theurl M, Jeschke J, Beer AG, Albrecht K, Gander R, Rong S, Vasiljevic D, Egger M, Wolf AM, Frauscher S, Koller B, Tancevski I, Patsch JR, Schratzberger P, Piza-Katzer H, Ritsch A, Bahlmann FH, Fischer-Colbrie R, Wolf D, Kirchmair R.

Circ Res 9 Nov 2009; 105(10)994. 1002

Effects of weight loss induced by bariatric surgery on hepatic adipocytokine expression

Moschen AR, Molnar C, Wolf AM, Weiss H, Graziadei I, Kaser S, Ebenbichler CF, Stadlmann S, Moser PL, Tilg H.

J Hepato 1 Oct 2009; 51(4)765-77.

The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo.

Wolf AM, Eller K, Zeiser R, Dürr C, Gerlach UV, Sixt M, Markut L, Gastl G, Rosenkranz AR, Wolf D.

J Immunol 15 Sep 2009; 183(6)3751-60.

The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation.

Evenou JP, Wagner J, Zenke G, Brinkmann V, Wagner K, Kovarik J, Welzenbach KA, Weitz-Schmidt G, Guntermann C, Towbin H, Cottens S, Kaminski S, Letschka T, Lutz-Nicoladoni C, Gruber T, Hermann-Kleiter N, Thuille N, Baier G.

Journal of Pharmacological Experimental Therapy 1 Sep 2009; 330(3)792-801.

Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ ALL and CML cells in vitro.

Kircher B, Schumacher P, Petzer A, Hoflehner E, Haun M, Wolf AM, Nachbaur D, Gastl G.

Eur J Haematol 1 Jul 2009; 83(1)48-56.

Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.

Spoden GA, Rostek U, Lechner S, Mitterberger M, Mazurek S, Zwerschke W.

Exp Cell Res. 27 Jun 2009; (). [Epub ahead of print]

Repression of the BH3-only molecule PMAIP1/Noxa impairs glucocorticoid sensitivity of acute lymphoblastic leukemia cells

Ploner C, Rainer J, Lobenwein S, Geley S, Kofler R.

Apoptosis 1 Jun 2009; 14(6)821-8.

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo.

Gruber T, Hermann-Kleiter N, Pfeifhofer-Obermair C, Lutz-Nicoladoni C, Thuille N, Letschka T, Barsig J, Baudler M, Li J, Metzler B, Nüsslein-Hildesheim B, Wagner J, Leitges M, Baier G.

Molecular Immunology 1 Jun 2009; 46(10)2071-9.

Intratumoral interferon regulatory factor (IRF)-1 but not IRF-2 is of relevance in predicting patient outcome in ovarian cancer.

Zeimet AG, Reimer D, Wolf D, Fiegl H, Concin N, Wiedemair A, Wolf AM, Rumpold H, Müller-Holzner E, Marth C.

Int J Cancer 15 May 2009; 124(10)2353-60.

Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis.

Obexer P, Hagenbuchner J, Unterkircher T, Sachsenmaier N, Seifarth C, Böck G, Porto V, Geiger K, Ausserlechner M.

Mol Biol Cell 1 May 2009; 20(7)2041-8.

Levels of glucocorticoid receptor and its ligand determine sensitivity and kinetics of glucocorticoid-induced leukemia apoptosis.

Gruber G, Carlet M, Türtscher E, Meister B, Irving JA, Ploner C, Kofler R.

Leukemia 1 Apr 2009; 23(4)820-3.

Glucocorticoid-regulated microRNAs and mirtrons in acute lymphoblastic leukaemia

Rainer J, Ploner C, Jesacher S, Ploner A, Eduardoff M, Mansha M, Wasim M, Panzer-Grümayer R, Trajanoski Z, Niederegger H, Kofler R.

Leukemia 1 Apr 2009; 23(4)746-52.

The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2.

Spoden GA, Morandell D, Ehehalt D, Fiedler M, Jansen-Dürr P, Hermann M, Zwerschke W.

J Cell Biochem 10 Feb 2009; 107(2)293-302.

Prognostic significance of 14-3-3sigma expression in oral squamous cell carcinoma (OSCC).

Laimer K, Blassnig N, Spizzo G, Kloss F, Rasse M, Obrist P, Schäfer G, Perathoner A, Margreiter R, Amberger A.

Oral Oncol 1 Feb 2009; 45(2)127-34.

The involvement of the fractalkine receptor in the transmigration of neuroblastoma cells through bone-marrow endothelial cells.

Nevo I, Sagi-Assif O, Meshel T, Ben-Baruch A, Jöhrer K, Greil R, Trejo LE, Kharenko O, Feinmesser M, Yron I, Witz IP.

Cancer Lett 8 Jan 2009; 273(1)127-39.

Silencing von Cbl-b, Oncotyrol: neues Konzept der Krebsimmuntherapie

Gruber, T., Lutz-Nicoladoni, C., Hanisch, C

JATROS Hämatologie und Onkologie 1 Jan 2009; 3()50-51.

PKC-theta selectively controls the adhesion-stimulating molecule Rap1.

Letschka T, Kollmann V, Pfeifhofer-Obermair C, Lutz-Nicoladoni C, Obermair GJ, Fresser F, Leitges M, Hermann-Kleiter N, Kaminski S, Baier G.

Blood 1 Dec 2008; 112(12)4617-27.

High expression of TROP2 correlates with poor prognosis in pancreatic cancer.

Fong D, Moser P, Krammel C, Gostner JM, Margreiter R, Mitterer M, Gastl G, Spizzo G.

Br J Cancer 21 Oct 2008; 99(8)1290-5.

Human papillomavirus type 45 E7 is a transforming protein inducing retinoblastoma protein degradation and anchorage-independent cell cycle progression.

Morandell, D., Rostek, U., Bouvard, V., Campo-Fernández, B., Fiedler, M. Jansen-Dürr, P., and W. Zwerschke.

Virology 15 Sep 2008; 379(1)20-9.

The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.

Hermann-Kleiter N, Gruber T, Lutz-Nicoladoni C, Thuille N, Fresser F, Labi V, Schiefermeier N, Warnecke M, Huber L, Villunger A, Eichele G, Kaminski S, Baier G.

Immunity 15 Aug 2008; 29(2)205-16.

Premature senescence of human endothelial cells induced by inhibition of glutaminase.

Unterluggauer H, Mazurek S, Lener B, Hütter E, Eigenbrodt E, Zwerschke W, Jansen-Dürr P.

Biogerontology 1 Aug 2008; 9(4)247-59. Epub 2008 Mar 4

Myocardial ischaemia-reperfusion injury in haematopoietic cell-restricted beta1 integrin knockout mice.

Metzler B, Haubner B, Conci E, Voelkl J, Jehle J, Bauer M, Wolf D, Pachinger O, Xu Q.

Exp Physiol 1 Jul 2008; 93(7)825-33.

Insulin-like growth factor-induced signals activate mitochondrial respiration.

Unterluggauer H, Hütter E, Viertler HP, Jansen-Dürr P.

Biotechnol J 1 Jun 2008; 3(6)813-6. Journal not listed

Mesenchymal stem cells as cellular immunosuppressants.

Wolf D, Wolf AM.

Lancet 10 May 2008; 371(9624)1553-4.

Differential effects of rapamycin in anti-GBM glomerulonephritis.

Hochegger K, Jansky GL, Soleiman A, Wolf AM, Tagwerker A, Seger C, Griesmacher A, Mayer G, Rosenkranz AR.

J Am Soc Nephrol 1 May 2008; 19(8)1520-9.

Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation.

Spoden GA, Mazurek S, Morandell D, Bacher N, Ausserlechner MJ, Jansen-Dürr P, Eigenbrodt E, Zwerschke W.

Int J Cancer 18 Apr 2008; 123(2)312-321. [Epub ahead of print]

Endothelial cells from cord blood CD133(+)CD34(+) progenitors share phenotypic, functional and gene expression profile similarities with lymphatics.

Nguyen VA, Fürhapter C, Obexer P, Stössel H, Romani N, Sepp N.

J Cell Mol Med. 9 Apr 2008; (). [Epub ahead of print]Click here to read

The Dickkopf-homolog 3 is expressed in tumor endothelial cells and supports capillary formation.

Untergasser G, Steurer M, Zimmermann M, Hermann M, Kern J, Amberger A, Gastl G, Gunsilius E.

Int J Cancer. 1 Apr 2008; 122(7)1539-47.

The effect of secretory leukocyte protease inhibitor (SLPI) on ischemia/reperfusion injury in cardiac transplantation.

Schneeberger S, Hautz T, Wahl SM, Brandacher G, Sucher R, Steinmassl O, Steinmassl P, Wright CD, Obrist P, Werner ER, Mark W, Troppmair J, Margreiter R, Amberger A.

Am J Transplant. 1 Apr 2008; 8(4)773-82.

Possible role for gene expression profiling in predicting responses to conventional or targeted drugs in patients with chronic myeloid leukemia.

Schmidt S, Gastl G, Wolf D.

Leuk Lymphoma 1 Apr 2008; 49(4)643-7.

Autocrine formation of hepcidin induces iron retention in human monocytes.

Theurl I, Theurl M, Seifert M, Mair S, Nairz M, Rumpold H, Zoller H, Bellmann-Weiler R, Niederegger H, Talasz H, Weiss G.

Blood 15 Feb 2008; 111(4)2392-9.

The BCL2 rheostat in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia.

Ploner C, Rainer J, Niederegger H, Eduardoff M, Villunger A, Geley S, Kofler R.

Epub 2007 Nov 29. 1 Feb 2008; 22(2)7-370.

Dickkopf-3 as a new potential marker for neoangiogenesis in colorectal cancer: expression in cancer tissue and adjacent non-cancerous tissue.

Zitt M, Untergasser G, Amberger A, Moser P, Stadlmann S, Zitt M, Müller HM, Mühlmann G, Perathoner A, Margreiter R, Gunsilius E and Öfner D.

Dis Markers 1 Feb 2008; 24(2)101-9.

TROP2: a novel prognostic marker in squamous cell carcinoma of the oral cavity.

Fong D, Spizzo G, Gostner JM, Gastl G, Moser P, Krammel C, Gerhard S, Rasse M, Laimer K.

Mod Pathol. 1 Feb 2008; 21(2)186-91.

SFRP2 methylation in fecal DNA-a marker for colorectal polyps.

Oberwalder M, Zitt M, Wöntner C, Fiegl H, Goebel G, Zitt M, Köhle O, Mühlmann G, Amberger A, Öfner D, Margreiter R and Müller HM.

Int J Colorectal Dis 1 Jan 2008; 23(1)15-9.

EpCAM expression in squamous cell carcinoma of the oral cavity: frequency and relationship to clinicopathologic features.

Laimer K, Fong D, Gastl G, Obrist P, Kloss F, Tuli T, Gassner R, Rasse M, Norer B, Spizzo G.

Oral Oncol 1 Jan 2008; 44(1)72-7.

Quantification of circulating endothelial and progenitor cells: comparison of quantitative PCR and four-channel flow cytometry.

Steurer M, Kern J, Zitt M, Amberger A, Bauer M, Gastl G, Untergasser G, Gunsilius E.

BMC Res Notes 1 Jan 2008; 28(1)71.

Human papillomavirus type 16 E7 oncoprotein inhibits apoptosis mediated by nuclear insulin-like growth factor-binding protein-3 by enhancing its ubiquitin/proteasome-dependent degradation.

Santer FR, Moser B, Spoden GA, Jansen-Dürr P, Zwerschke W.

Carcinogenesis 1 Dec 2007; 28()2511-20.

High-risk human papillomavirus E7 oncoprotein detection in cervical squamous cell carcinoma.

Ressler S, Scheiden R, Dreier K, Laich A, Müller-Holzner E, Pircher H, Morandell D, Stein I, Viertler HP, Santer FR, Widschwendter A, Even J, Jansen-Dürr P, Capesius C, Zwerschke W.

Clin Cancer Res 1 Dec 2007; 13()7067-72.

Bilirubin inhibits tumor cell growth via activation of ERK.

Ollinger R, Kogler P, Troppmair J, Hermann M, Wurm M, Drasche A, Königsrainer I, Amberger A, Weiss H, Ofner D, Bach FH, Margreiter R.

Cell Cycle 1 Dec 2007; 6(24)3078-85.

STAT1 activation in squamous cell cancer of the oral cavity: a potential predictive marker of response to adjuvant chemotherapy.

Laimer K, Spizzo G, Obrist P, Gastl G, Brunhuber T, Schäfer G, Norer B, Rasse M, Haffner MC, Doppler W.

Cancer 15 Jul 2007; 110(2)326-33.

Lipocalin-2 regulates the inflammatory response during ischemia and reperfusion of the transplanted heart

Aigner F, Maier HT, Schwelberger HG, Wallnöfer EA, Amberger A, Obrist P, Berger T, Mak TW, Maglione M, Margreiter R, Schneeberger S, Troppmair J.

Am J Transplant 1 Apr 2007; 7(4)779-88.

FKHRL1- mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells.

Obexer P, Geiger K, Ambros PF, Meister B, Ausserlechner MJ.

Cell Death Differ. 1 Mar 2007; 14(3)534-47.

Methylation status of the Ep-CAM promoter region in human breast cancer cell lines and breast cancer tissue.

Spizzo G, Gastl G, Obrist P, Fong D, Haun M, Grunewald K, Parson W, Eichmann C, Millinger S, Fiegl H, Margreiter R, Amberger A.

Cancer Lett. 8 Feb 2007; 246(1-2)253-61. Epub 2006 Apr 18.

High EGFR expression predicts poor prognosis in patients with squamous cell carcinoma of the oral cavity and oropharynx: a TMA-based immunohistochemical analysis.

Laimer K, Spizzo G, Gastl G, Obrist P, Brunhuber T, Fong D, Barbieri V, Jank S, Doppler W, Rasse M, Norer B.

Oral Oncol. 1 Feb 2007; 43(2)193-8. Epub 2006 Jul 18.

Identification, tissue expression, and glucocorticoid responsiveness of alternative first exons of the human glucocorticoid receptor.

Presul E, Schmidt S, Kofler R, Helmberg A.

J Mol Endocrinol. 1 Feb 2007; 38(1-2)79-90.

DNA methylation in colorectal cancer – impact on screening and therapy monitoring modalities?

Zitt M, Zitt M, Muller HM.

Dis markers 1 Jan 2007; 23(1-2)51-71.

High-risk HPV E7 oncoprotein expression in cervical squamous cell carcinoma.

Ressler, S., Scheiden, R., Dreier, K., Laich, A., Müller-Holzner, E., Pircher, H., Morandell, D., Stein, I., Viertler, H.P., Santer, F.R., Widschwendter, A., Even, J., Jansen-Dürr, P., Capesius, C. and W. Zwerschke

Clin Can Res. 1 Jan 2007; (13)7067-7072.

The human papillomavirus type 16 E7 oncoprotein inhibits apoptosis induced by nuclear insulin-like growth factor binding protein-3 by inducing its ubiquitin/proteasome-dependent degradation.

Santer, F., Moser, B., Spoden, G.A., Jansen-Dürr, P., and W. Zwerschke.

Carcinogenesis 1 Jan 2007; 28()2511-2520.

DNA methylation in colorectal cancer - Impact on screening and therapy monitoring modalities?

Zitt M, Zitt M, Muller HM.

Dis Markers. 1 Jan 2007; 23(1-2)51-71.

Identification of the FHL2 transcriptional coactivator as a new functional target of the E7 oncoprotein of human papillomavirus type 16.

Campo-Fernandez B, Morandell D, Santer FR, Zwerschke W, Jansen-Durr P.

J Virol. 1 Jan 2007; 81(2)1027-32. Epub 2006 Nov 8.

Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor.

Schmidt S, Irving JA, Minto L, Matheson E, Nicholson L, Ploner A, Parson W, Kofler A, Amort M, Erdel M, Hall A, Kofler R.

FASEB J. 1 Dec 2006; 20(14)2600-2. Epub 2006 Oct 31.

Overexpression of epithelial cell adhesion molecule (Ep-CAM) is an independent prognostic marker for reduced survival of patients with epithelial ovarian cancer.

Spizzo G, Went P, Dirnhofer S, Obrist P, Moch H, Baeuerle PA, Mueller-Holzner E, Marth C, Gastl G, Zeimet AG.

Gynecol Oncol. 1 Nov 2006; 103(2)483-8. Epub 2006 May 6.

Disseminated tumor cells in peripheral blood: a novel marker for therapy response in locally advanced rectal cancer patients undergoing preoperative chemoradiation.

Zitt M, Zitt M, Muller HM, Dinnewitzer AJ, Schwendinger V, Goebel G, De Vries A, Amberger A, Weiss H, Margreiter R, Ofner D, Oberwalder M.

Dis Colon Rectum. 1 Oct 2006; 49(10)14784-91.

Antitumoral activity of interferon-gamma involved in impaired immune function in cancer patients.

Brandacher G, Winkler C, Schroecksnadel K, Margreiter R, Fuchs D.

Curr Drug Metab. 1 Aug 2006; 7(6)599-612. Review

A retroviral expression system based on tetracycline-regulated tricistronic transactivator/repressor vectors for functional analyses of antiproliferative and toxic genes.

Ausserlechner MJ, Obexer P, Deutschmann A, Geiger K, Kofler R.

Mol Cancer Ther. 1 Aug 2006; 5(8)1927-34.

CARMAweb: comprehensive R- and bioconductor-based web service for microarray data analysis.

Rainer J, Sanchez-Cabo F, Stocker G, Sturn A, Trajanoski Z.

Nucleic Acids Res. 1 Jul 2006; 34(Web Server)498-503.

Ep-CAM expression in pancreatic and ampullary carcinomas: frequency and prognostic relevance.

Fong D, Steurer M, Obrist P, Barbieri V, Margreiter R, Amberger A, Laimer K, Gastl G, Tzankov A, Spizzo G

J Clin Pathol. 14 Jun 2006; ().

Purification and characterisation of the E7 oncoproteins of the high-risk human papillomavirus types 16 and 18.

Fiedler M, Campo-Fernandez B, Laich A, Moser B, Stockl P, Jansen-Durr P, Zwerschke W.

J Virol Methods. 1 Jun 2006; 134(1-2)30-5. Epub 2005 Dec 27.

Suppression of KCMF1 by constitutive high CD99 expression is involved in the migratory ability of Ewing's sarcoma cells.

Kreppel M, Aryee DN, Schaefer KL, Amann G, Kofler R, Poremba C, Kovar H.

Oncogene. 4 May 2006; 25(19)2795-800.

A role of TRAIL in killing osteoblasts by myeloma cells.

Tinhofer I, Biedermann R, Krismer M, Crazzolara R, Greil R.

FASEB J. 1 Apr 2006; 20(6)759-61. Epub 2006 Jan 25.

Nuclear insulin-like growth factor binding protein-3 induces apoptosis and is targeted to ubiquitin/proteasome-dependent proteolysis.

Santer FR, Bacher N, Moser B, Morandell D, Ressler S, Firth SM, Spoden GA, Sergi C, Baxter RC, Jansen-Durr P, Zwerschke W.

Cancer Res. 15 Mar 2006; 66(6)3024-33.

Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells.

Bacher N, Tiefenthaler M, Sturm S, Stuppner H, Ausserlechner MJ, Kofler R, Konwalinka G.

Br J Haematol. 1 Mar 2006; 132(5)615-22.

Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia.

Schmidt S, Rainer J, Riml S, Ploner C, Jesacher S, Achmuller C, Presul E, Skvortsov S, Crazzolara R, Fiegl M, Raivio T, Janne OA, Geley S, Meister B, Kofler R.

Blood. 1 Mar 2006; 107(5)2061-9. Epub 2005 Nov 17.

Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.

Brandacher G, Perathoner A, Ladurner R, Schneeberger S, Obrist P, Winkler C, Werner ER, Werner-Felmayer G, Weiss HG, Gobel G, Margreiter R, Konigsrainer A, Fuchs D, Amberger A.

Clin Cancer Res. 15 Feb 2006; 12(4)1144-51.

Disseminated tumor cells in peripheral blood: a novel marker for therapy response in locally advanced rectal cancer patients undergoing preoperative chemoradiation

Zitt M, Zitt M, Muller HM, Dinnewitzer AJ, Schwendinger V, Goebel G, De Vries A, Amberger A, Weiss H, Margreiter R, Ofner D, Oberwalder M.

Dis Colon Rectum 1 Jan 2006; 49(1)1484-91.

Response of human peritoneal mesothelial cells to inflammatory injury is regulated by interleukin-1beta and tumor necrosis factor-alpha.

Stadlmann S, Pollheimer J, Renner K, Zeimet AG, Offner FA, Amberger A.

Wound Repair Regen. 1 Jan 2006; 14(2)187-94.

Expression of the high-risk human papillomavirus type 18 and 45 E7 oncoproteins in cervical carcinoma biopsies.

Fiedler M, Ressler S, Campo-Fernandez B, Laich A, Jansen L, Widschwendter A, Viertler HP, Bacher N, Morandell D, Muller-Holzner E, Durst M, Jansen-Durr P, Zwerschke W.

J Gen Virol. 1 Dec 2005; 86(Pt 12)3235-41.

Apoptosis resistance of senescent human fibroblasts is correlated with the absence of nuclear IGFBP-3.

Hampel B, Wagner M, Teis D, Zwerschke W, Huber LA, Jansen-Durr P.

Aging Cell. 1 Dec 2005; 4(6)325-30.

CXCR4 chemokine receptors, histone deacetylase inhibitors and acute lymphoblastic leukemia.

Crazzolara R, Bernhard D.

Leuk Lymphoma. 1 Nov 2005; 46(11)1545-51.

Ovarian carcinoma cells and IL-1beta-activated human peritoneal mesothelial cells are possible sources of vascular endothelial growth factor in inflammatory and malignant peritoneal effusions.

Stadlmann S, Amberger A, Pollheimer J, Gastl G, Offner FA, Margreiter R, Zeimet AG.

Gynecol Oncol. 1 Jun 2005; 97(3)784-9.

G1 arrest by p16INK4A uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression.

Ausserlechner MJ, Obexer P, Geley S, Kofler R.

Leukemia. 1 Jun 2005; 19(6)1051-7.

Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation.

Hainz U, Obexer P, Winkler C, Sedlmayr P, Takikawa O, Greinix H, Lawitschka A, Potschger U, Fuchs D, Ladisch S, Heitger A.

Blood. 15 May 2005; 105(10)4127-34. Epub 2005 Jan 27

14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients.

Perathoner A, Pirkebner D, Brandacher G, Spizzo G, Stadlmann S, Obrist P, Margreiter R, Amberger A.

Clin Cancer Res. 1 May 2005; 11(9)3274-9.

Polyacetylenes from the Apiaceae vegetables carrot, celery, fennel, parsley, and parsnip and their cytotoxic activities.

Zidorn C, Johrer K, Ganzera M, Schubert B, Sigmund EM, Mader J, Greil R, Ellmerer EP, Stuppner H.

J Agric Food Chem. 6 Apr 2005; 53(7)2518-23.

Up-regulation of functional chemokine receptor CCR3 in human renal cell carcinoma.

Johrer K, Zelle-Rieser C, Perathoner A, Moser P, Hager M, Ramoner R, Gander H, Holtl L, Bartsch G, Greil R, Thurnher M.

Clin Cancer Res. 1 Apr 2005; 11(7)2459-65.

Cancer cell line identification by short tandem repeat profiling: power and limitations.

Parson W, Kirchebner R, Muhlmann R, Renner K, Kofler A, Schmidt S, Kofler R.

FASEB J. 1 Mar 2005; 19(3)434-6. Epub 2005 Jan 6.

Glucocorticoid-induced apoptosis and glucocorticoid resistance in acute lymphoblastic leukemia.

Ploner C, Schmidt S, Presul E, Renner K, Schrocksnadel K, Rainer J, Riml S, Kofler R.

J Steroid Biochem Mol Biol. 1 Feb 2005; 93(2-5)153-60. Epub 2005 Jan 26.

Circulating nucleic acids in plasma or serum (CNAPS) as prognostic and predictive markers in patients with solid neoplasias.

Goebel G, Zitt M, Zitt M, Muller HM.

Dis Markers 1 Jan 2005; 21(3)105-20.

Sensitization of colon cancer cell lines to butyrate-mediated proliferation inhibition by combined application of indomethacin and nordihydroguaiaretic acid.

Galfi P, Neogrady Z, Amberger A, Margreiter R, Csordas A.

Cancer Detect Prev. 1 Jan 2005; 29(3)276-85. Epub 2005 Feb 17.

Inhibition by cytoplasmic nucleotides of a new cation channel in freshly isolated human and rat type II pneumocytes.

Mair N, Frick M, Bertocchi C, Haller T, Amberger A, Weiss H, Margreiter R, Streif W, Dietl P.

Am J Physiol Lung Cell Mol Physiol. 1 Dec 2004; 287(6)1284-92.

Teratocarcinosarcoma of the oral cavity.

Crazzolara R, Puelacher W, Ninkovic M, Zelger B, Buchberger W, Meister B, Zimmerhackl LB, Klein-Franke A.

Pediatr Blood Cancer. 1 Nov 2004; 43(6)687-91.

Is higher income and educational status associated with poorer outcome in patients with Hodgkin's disease?

Holzner B, Fischhofer M, Kemmler G, Kopp M, Sperner-Unterweger B, Krugmann J, Dirnhofer S, Greil R.

Eur J Haematol. 1 Nov 2004; 73(5)318-24.

Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance.

Schmidt S, Rainer J, Ploner C, Presul E, Riml S, Kofler R.

Cell Death Differ. 1 Jul 2004; 11(Suppl 1)45-55.

Glucocorticoid receptor heterozygosity combined with lack of receptor auto-induction causes glucocorticoid resistance in Jurkat acute lymphoblastic leukemia cells.

Riml S, Schmidt S, Ausserlechner MJ, Geley S, Kofler R.

Cell Death Differ. 1 Jul 2004; 11(Suppl 1)65-72.

Quality of life of patients with chronic lymphocytic leukemia: results of a longitudinal investigation over 1 yr.

Holzner B, Kemmler G, Kopp M, Nguyen-Van-Tam D, Sperner-Unterweger B, Greil R.

Eur J Haematol. 1 Jun 2004; 72(6)381-9.

High level HPV-16 E7 oncoprotein expression correlates with reduced pRb-levels in cervical biopsies.

Fiedler M, Muller-Holzner E, Viertler HP, Widschwendter A, Laich A, Pfister G, Spoden GA, Jansen-Durr P, Zwerschke W.

FASEB J. 1 Jun 2004; 18(10)1120-2. pub 2004 May 20.

Unfavourable prognosis of patients with trisomy 18q21 detected by fluorescence in situ hybridisation in t(11;18) negative, surgically resected, gastrointestinal B cell lymphomas.

Krugmann J, Tzankov A, Dirnhofer S, Fend F, Greil R, Siebert R, Erdel M.

J Clin Pathol. 1 Apr 2004; 57(4)360-4.

Aberrant tetranectin expression in human breast carcinomas as a predictor of survival.

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J Clin Pathol. 1 Apr 2004; 57(4)417-21.

Transendothelial migration of myeloma cells is increased by tumor necrosis factor (TNF)-alpha via TNF receptor 2 and autocrine up-regulation of MCP-1.

Johrer K, Janke K, Krugmann J, Fiegl M, Greil R.

Clin Cancer Res. 15 Mar 2004; 10(6)1901-10.

Reduction of intracellular pH inhibits constitutive expression of cyclooxygenase-2 in human colon cancer cells.

Pirkebner D, Fuetsch M, Wittmann W, Weiss H, Haller T, Schramek H, Margreiter R, Amberger A.

J Cell Physiol. 1 Feb 2004; 198(2)295-301.

Cyclin D3 and c-MYC control glucocorticoid-induced cell cycle arrest but not apoptosis in lymphoblastic leukemia cells.

Ausserlechner MJ, Obexer P, Bock G, Geley S, Kofler R.

Cell Death Differ. 1 Feb 2004; 11(2)165-74.

Functional analysis of the mutated Epstein-Barr virus oncoprotein LMP1(69del): implications for a new role of naturally occurring LMP1 variants.

Larcher C, Bernhard D, Schaadt E, Adler B, Ausserlechner MJ, Mitterer M, Huemer HP.

Haematologica. 1 Dec 2003; 88(12)1324-35.

A conceptual view on glucocorticoid-lnduced apoptosis, cell cycle arrest and glucocorticoid resistance in lymphoblastic leukemia.

Renner K, Ausserlechner MJ, Kofler R.

Curr Mol Med. 1 Dec 2003; 3(8)707-17.

Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.

Zwerschke W, Mazurek S, Stockl P, Hutter E, Eigenbrodt E, Jansen-Durr P.

Biochem J. 1 Dec 2003; 376(Pt 2)403-11.

Disruption of the integrity of human peritoneal mesothelium by interleukin-1beta and tumor necrosis factor-alpha.

Stadlmann S, Raffeiner R, Amberger A, Margreiter R, Zeimet AG, Abendstein B, Moser PL, Mikuz G, Klosterhalfen B, Offner FA.

Virchows Arch. 1 Nov 2003; 443(5)678-85. Epub 2003 Jul 26.

Cytokine-regulated expression of collagenase-2 (MMP-8) is involved in the progression of ovarian cancer.

Stadlmann S, Pollheimer J, Moser PL, Raggi A, Amberger A, Margreiter R, Offner FA, Mikuz G, Dirnhofer S, Moch H.

Eur J Cancer. 1 Nov 2003; 39(17)2499-505.

Heparanase-1 gene expression in normal, hyperplastic and neoplastic prostatic tissue.

Stadlmann S, Moser PL, Pollheimer J, Steiner P, Krugmann J, Dirnhofer S, Mikuz G, Margreiter R, Amberger A.

Eur J Cancer. 1 Oct 2003; 39(15)2229-33.

Senescence-associated cell death of human endothelial cells: the role of oxidative stress.

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Exp Gerontol. 1 Oct 2003; 38(10)1149-60.

Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells.

Renner K, Amberger A, Konwalinka G, Kofler R, Gnaiger E.

Biochim Biophys Acta. 23 Sep 2003; 1642(1-2)115-23.

Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools.

Greil R, Anether G, Johrer K, Tinhofer I.

J Leukoc Biol. 1 Sep 2003; 74(3)311-30.

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J Endocrinol. 1 Jul 2003; 178(1)19-27.

Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells.

Bernhard D, Schwaiger W, Crazzolara R, Tinhofer I, Kofler R, Csordas A.

Cancer Lett. 10 Jun 2003; 195(2)193-9.

Tetrocarcin-A--induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2--independent pathway.

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Blood. 1 Jun 2003; 101(11)4561-8. Epub 2003 Jan 30.

Prognostic significance of CD20 expression in classical Hodgkin lymphoma: a clinicopathological study of 119 cases.

Tzankov A, Krugmann J, Fend F, Fischhofer M, Greil R, Dirnhofer S.

Clin Cancer Res. 1 Apr 2003; 9(4)1381-6.

Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survival.

Spizzo G, Gastl G, Wolf D, Gunsilius E, Steurer M, Fong D, Amberger A, Margreiter R, Obrist P.

Br J Cancer. 24 Feb 2003; 88(4)574-8.

Tuning the rheostat of the myelopoietic system via Fas and TRAIL.

Greil R, Anether G, Johrer K, Tinhofer I.

Crit Rev Immunol. 1 Jan 2003; 23(4)301-22.

Histone deacetylase inhibitors potently repress CXCR4 chemokine receptor expression and function in acute lymphoblastic leukaemia.

Crazzolara R, Johrer K, Johnstone RW, Greil R, Kofler R, Meister B, Bernhard D.

Br J Haematol. 1 Dec 2002; 119(4)965-9.

Gene expression profiling of prolonged cold ischemia and reperfusion in murine heart transplants.

Amberger A, Schneeberger S, Hernegger G, Brandacher G, Obrist P, Lackner P, Margreiter R, Mark W.

Transplantation. 27 Nov 2002; 74(10)1441-9.

Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in human neuroblastomas.

Crazzolara R, Abrederis K, Kreczy A, Meister B.

Med Pediatr Oncol. 1 Aug 2002; 39(2)146.

Stressful death of T-ALL tumor cells after treatment with the anti-tumor agent Tetrocarcin-A.

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FASEB J. 1 Aug 2002; 16(10)1295-7. Epub 2002 Jun 7.

Regulation and function of the cytokine-inducible SH-2 domain proteins, CIS and SOCS3, in mammary epithelial cells.

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Mol Endocrinol. 1 Jul 2002; 16(7)1680-95.

Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells.

Ruefli AA, Bernhard D, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.

Int J Cancer. 10 May 2002; 99(2)292-8.

Mitochondrial function in glucocorticoid triggered T-ALL cells with transgenic bcl-2 expression.

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Mol Biol Rep. 1 Jan 2002; 29(1-2)97-101.

Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption.

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Mol Biol Rep. 1 Jan 2002; 29(1-2)83-7.

Mechanisms of brain injury in infantile child abuse.

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Lancet. 15 Dec 2001; 358(9298)2082-3.

High expression of the chemokine receptor CXCR4 predicts extramedullary organ infiltration in childhood acute lymphoblastic leukaemia.

Crazzolara R, Kreczy A, Mann G, Heitger A, Eibl G, Fink FM, Mohle R, Meister B.

Br J Haematol. 1 Dec 2001; 115(3)545-53.

Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7.

Mazurek S, Zwerschke W, Jansen-Durr P, Eigenbrodt E.

Oncogene. 18 Oct 2001; 20(47)6891-8.

Update on white matter genetic disorders.

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Pediatr Neurol. 1 Oct 2001; 25(4)348.

Effects of all-trans-retinoic acid and all-trans-retinoyl glucuronide in two in vitro systems of distinct biological complexity.

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Arch Toxicol. 1 Oct 2001; 75(8)497-504.

Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts.

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The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.

Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.

Proc Natl Acad Sci U S A. 11 Sep 2001; 98(19)10833-8. Epub 2001 Sep 4.

ESMO recommendations for the application of haematopoietic growth factors (hGFs).

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Ann Oncol. 1 Sep 2001; 12(9)1219-20.

Increased lactate production follows loss of mitochondrial membrane potential during apoptosis of human leukaemia cells.

Tiefenthaler M, Amberger A, Bacher N, Hartmann BL, Margreiter R, Kofler R, Konwalinka G.

Br J Haematol. 2001 Sep;114(3):574-80. 1 Sep 2001; 117(3)574-80.

Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis.

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Exp Gerontol. 1 Aug 2001; 36(8)1327-47.

Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status.

Pallis M, Grundy M, Turzanski J, Kofler R, Russell N.

Blood. 15 Jul 2001; 98(2)405-13.

Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells.

Weiss H, Amberger A, Widschwendter M, Margreiter R, Ofner D, Dietl P.

Int J Cancer. 15 Jun 2001; 92(6)877-80.

The cell cycle inhibitor p16(INK4A) sensitizes lymphoblastic leukemia cells to apoptosis by physiologic glucocorticoid levels.

Ausserlechner MJ, Obexer P, Wiegers GJ, Hartmann BL, Geley S, Kofler R.

J Biol Chem. 15 Jun 2001; 276(24)10984-9.

Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.

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Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: role of pyruvate kinase type M2 and the glycolytic-enzyme complex.

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Biochem J. 15 May 2001; 356(Pt 1)247-56.

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

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Induction of apoptosis in cervical carcinoma cells by peptide aptamers that bind to the HPV-16 E7 oncoprotein.

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FASEB J. 1 Mar 2001; 15(3)592-4. Epub 2001 Jan 19.

Interleukin-15 as a potential costimulatory cytokine in CD154 gene therapy of chronic lymphocytic leukemia.

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Blood. 15 Jan 2001; 99(2)722-3.

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Mannhardt B, Weinzimer SA, Wagner M, Fiedler M, Cohen P, Jansen-Durr P, Zwerschke W.

Mol Cell Biol. 1 Sep 2000; 20(17)6483-95.

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Histochem Cell Biol. 1 May 2000; 114(1)1-7. Review

Peptide aptamers as isotype-specific inhibitors of the metabolic keyregulator pyruvate kinase subtype M2.

Spoden, G. A., Mazurek, S., Morandell, D., Bacher, N., Ausserlechner, M., Jansen-Dürr, P., Eigenbrodt E., and W. Zwerschke.

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IL-4 inhibits the TNF-alpha induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-alpha to induce apoptotic and cytokine responses by RCC: implications for antitumor immune responses.

Falkensammer C, Johrer K, Gander H, Ramoner R, Putz T, Rahm A, Greil R, Bartsch G, Thurnher M.

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Insulin-like Growth Factor-binding Protein-3 in Osteosarcomas and Normal Bone Tissues.

Ressler S, Radhi J, Aigner T, Loo C, Zwerschke W, Sergi C.

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